Hydrolyzed Collagen |92113-31-0

Ibisobanuro ku bicuruzwa:

Nyuma ya hydrolysis ya enzymatique ya kolagen, irashobora guhinduka hydrolyzed collagen (Hydrolyzed Collagen, izwi kandi nka peptide ya kolagen).

Kolagen polypeptide irimo ubwoko 19 bwa ​​aside amine.Kolagen (nanone yitwa kolagen) ni poroteyine yubatswe ya matrice idasanzwe kandi ni cyo kintu nyamukuru kigize matrice idasanzwe (ECM), ikaba igera kuri 85% by'ibikomoka kuri fibre ya kolagen.

Kolagen ni poroteyine igaragara hose mu mubiri w’inyamaswa, cyane cyane mu ngingo zihuza (amagufwa, karitsiye, uruhu, imitsi, gukomera, nibindi) 6%.

Mu binyabuzima byinshi byo mu nyanja, nk'uruhu rw'amafi, ibirimo poroteyine ndetse bigera kuri 80%.

Imikorere ya Hydrolyzed collagen

Hydrolyzed Collagen ikoreshwa cyane mu kwisiga, ifite imirimo nko kurwanya inkari, kwera, gusana, kuvomera, kweza, no kunoza uruhu rworoshye.

Hydrolyzed Collagen irashobora gukoreshwa mubicuruzwa byita kumubiri, bishobora gukora selile, kunoza imikorere yumubiri, kurwanya gusaza, kwirinda gusaza kwuruhu, kugabanya ibiro, kuzamura umubiri, kwagura amabere, nibindi.

Uburyo bwo kubyaza umusaruro Hydrolyzed Collagen

Hydrolyzed collagen ikurwa mu magufa no ku ruhu rw’inyamaswa zashyizwe mu kato k'ubuzima, kandi imyunyu ngugu iri mu magufa no ku ruhu ikavangwa na aside aside yo mu rwego rwo hejuru.Ingurube cyangwa amafi) nyuma yo kuvurwa na alkali cyangwa aside, amazi meza asukuye osmose akoreshwa mugukuramo poroteyine ya macromolecular ya kolagen ku bushyuhe runaka, hanyuma binyuze mumikorere idasanzwe ya hydrolysis ya hydrolysis, urunigi rwa macromolecular rucibwa neza, kandi rwuzuye kugumana Amatsinda meza ya aside amine, hanyuma ahinduke hydrolyzed collagen ifite uburemere bwa molekile ya 2000-5000 Daltons.

Igikorwa cyo kubyaza umusaruro kigera ku rwego rwo hejuru rwibikorwa by’ibinyabuzima no kweza binyuze mu kuyungurura byinshi no kuvanaho ion zanduye, kandi binyuze mu buryo bwa kabiri bwo kuboneza urubyaro harimo ubushyuhe bwo hejuru bwa 140 ° C kugira ngo ibinyabuzima biri munsi ya 100 / g (uru rwego rwa mikorobe irenze cyane 1000 / g yuburinganire bw’ibihugu by’Uburayi), kandi itera-yumishijwe binyuze muri granulation idasanzwe kugira ngo ikore cyane, ifu ya hydrolyzed ifu ya kolagen.Gushonga mumazi akonje, byoroshye kandi byoroshye.

Ibyiza bya Hydrolyzed Collagen

(1) Hydrolyzed collagen ifite amazi meza:

Kwinjiza amazi nubushobozi bwa poroteyine yo gufata cyangwa gukuramo amazi.Nyuma ya hydrolysis ya kolagenase, hakozwe hydrolyzed collagen, kandi umubare munini wamatsinda ya hydrophilique ugaragara, bigatuma kwiyongera kwinshi kwamazi.

(2) Ubushobozi bwa hydrolyzed collagen nibyiza:

Amazi meza ya poroteyine biterwa numubare wamatsinda ionizable hamwe nitsinda rya hydrophilique muri molekile yayo.Hydrolysis ya kolagen itera kumeneka kwa peptide, bikavamo amatsinda amwe ya hydrophilique.

Ubwiyongere bwumubare wa (nka -COOH, -NH2, -OH) bigabanya hydrophobicity ya proteine, byongera ubwinshi bwumuriro, byongera hydrophilique, kandi byongera amazi.

(3) Ubushobozi bwo gufata amazi menshi ya hydrolyzed collagen:

Ubushobozi bwo gufata amazi ya poroteyine bugira ingaruka ku kuba intungamubiri za poroteyine, ubwinshi bwa molekile, ubwoko bwa ion, ibintu bidukikije, n'ibindi, kandi ubusanzwe bigaragazwa n’igipimo cy’amazi gisigaye.

Mugihe urugero rwa hydrolysis ya kolagen yiyongera, igipimo cyo gufata amazi nacyo cyiyongera buhoro buhoro.

(4) Chemotaxis ya hydrolyzed collagen kuri fibroblast:

Prolyl-hydroxyproline izagaragara mu maraso ya periferiya nyuma yo gufata abantu ba hydrolyzed collagen, kandi prolyl-hydroxyproline irashobora gukangura uruhu Fibroblast ikura, ikongera umubare wa fibroblast yimuka mu ruhu, kunoza ihinduka ry’ingirabuzimafatizo, kwihutisha urujya n'uruza rw'amazi binyuze mu mazi. uruhu rwuruhu, ongera ubushobozi bwuruhu rwuruhu, kandi wirinde ko habaho iminkanyari yimbitse.

Gukoresha Hydrolyzed Collagen mumavuta yo kwisiga

Kolagen ihindurwamo hydrolyzed kugirango ibe hydrolyzed collagen, kandi imiterere ya molekuline hamwe nuburemere bwa molekile irahinduka, bikavamo impinduka mumikorere yayo nko kwinjiza amazi, gukomera, no gufata amazi.

Chemotaxis ya hydrolyzed collagen kuri fibroblast itera imikurire ya fibroblast kuruhu, byongera cyane ubwinshi bwa fibroblast, diameter ya kolagen fibre nubucucike, hamwe nijanisha rya sulfate ya dermatan muri decorin, bigatuma uruhu rukomera muburyo bwa tekinike Kwiyongera, kunoza imiterere yubukanishi, elastique, imbaraga zikomeye zo gutobora, hamwe no kunoza uruhu runini kandi rwimbitse.