Magnolia Cortex Gukuramo 2% Honokiol |35354-74-6

Magnolia officinalis ikuramo (izina ryicyongereza: Magnolia officinalis PE), ibikoresho bikora: na magnolol, magnolol, magnolol fenol yose.Inkomoko y'ibimera: Ikintu kigaragara mubikorwa bya antibacterial mugishishwa cya Magnolia officinalis Rehder et Wilson, ubuvuzi gakondo bwabashinwa.

Ibicuruzwa ni ifu yera ya kirisiti.Gushonga muri benzene, ether, chloroform, acetone, kudashonga mumazi, byoroshye gushonga mumashanyarazi ya alkali kugirango ubone umunyu wa sodium.Itsinda rya hydroxyl ya fenolike biroroshye kuba okiside, mugihe itsinda rya allyl ryoroshye kunyuramo reaction.

Ifite imbaraga zidasanzwe, zimara igihe kirekire zo kuruhura imitsi ningaruka zikomeye za antibacterial, zishobora kubuza gukusanya platine.

Mubuvuzi, ikoreshwa cyane nkumuti wa antibacterial na antifungal.Ibicuruzwa bigomba gufungwa kure yumucyo bikabikwa ahantu humye, hakonje kandi hahumeka neza.

Ingaruka ninshingano za Magnolia Cortex Gukuramo 2% Honokiol： 

Kurwanya inflammatory

Mubisubizo byumuriro, selile membrane fosifolipide irekura aside arachidonic (AA) ikorwa na fosifolipase A2.

Hariho inzira ebyiri zo guhinduranya AA, imwe nugukora prostaglandine na tromboxane kubikorwa bya cyclooxygenase (COX), naho ubundi ni ugukora prostaglandine na tromboxane ukoresheje cyclooxygenase (COX).Igikorwa cya lipoxygenase (LO) gitanga leukotriène (LT).

Honokiol yibanze cyane yabujije ibikorwa bya COX mu ngirabuzimafatizo zahungabanye, mu gihe ibuza inzira ya LO metabolike.Kubwibyo, honokiol ninzitizi ebyiri za COX na LO.

Ingaruka zo kurwanya inflammatory ya honokiol irashobora kuba ifitanye isano no kubuza inzira ebyiri za metabolike ya AA.Byongeye kandi, honokiol irashobora kubuza kurekura imisemburo ya lysosomal, igabanya ubwikorezi bwinkuta za capillary zikikije aho zaka, kandi ikabuza kwimuka kwa leukocyte no gukwirakwiza fibrous tissue.

Antioxydants

Magnolol na Honokiol bifite ingaruka zubusa za radical scavenging, zishobora gusiba parahydroxyl radicals na hydrogen peroxide.

Muri icyo gihe, irashobora kurinda ibikorwa byimisemburo yubuhumekero ya mitochondial irwanya imitekerereze ya NADPH iterwa na peroxidative stress, irwanya okiside hemolysis ya selile yamaraso itukura, kandi ikabuza lipide peroxidation.

Benshi muri vitro no mubushakashatsi bwa vivo basuzumye ibikorwa bya antioxydeant ya Magnolia officinalis ikuramo inshuro 1000 kuruta alpha-tocopherol.