L-Tryptophan | 73-22-3

Tryptophan (IUPAC-IUBMB mu magambo ahinnye: Trp cyangwa W; IUPACabbreviation: L-Trp cyangwa D-Trp; yagurishijwe kugirango ikoreshwe mu buvuzi nka Tryptan) ni imwe muri 22 acide amine na aside amine y'ingenzi mu mirire y'abantu, nk'uko bigaragazwa no gukura kwayo Ingaruka ku mbeba. Irimo kodegisi ya code isanzwe nka codon UGG. Gusa L-stereoisomer ya tryptophan ikoreshwa na proteine ​​yigisha cyangwa enzyme, ariko R -stereoisomer rimwe na rimwe ibonekaunbisanzwe byakozwe na peptide (urugero, ubumara bwo mu nyanja peptide contryphan) .Itandukaniro ryimiterere iranga tripitofani nuko irimo itsinda ryimikorere ya indole.

Hariho ibimenyetso byerekana ko urugero rwamaraso ya tripitofani idashobora guhinduka muguhindura imirire, ariko mugihe runaka, tryptophan yaboneka mububiko bwibiryo byubuzima nkinyongera yimirire.

Ubushakashatsi ku mavuriro bwerekanye ibisubizo bivanze ku bijyanye na tryptophan ikora neza imfashanyo yo gusinzira, cyane cyane ku barwayi basanzwe. Tryptophan yerekanye uburyo bunoze bwo kuvura ubundi buryo butandukanye busanzwe bujyanye na serotonine nkeya mu bwonko. By'umwihariko, tryptophan yerekanye amasezerano amwe nka antidepressant wenyine kandi nka "augmenter" imiti igabanya ubukana. Nyamara, kwizerwa kwibi bigeragezo byamavuriro byaribazwe kubera kubura kugenzura bisanzwe no kubisubiramo. Byongeye kandi, tryptophan ubwayo ntishobora kuba ingirakamaro mukuvura depression cyangwa izindi myumvire iterwa na serotonine, ariko irashobora kuba ingirakamaro mugusobanukirwa inzira yimiti izatanga icyerekezo gishya cyubushakashatsi kumiti.