L-Carnitine | 541-15-1

L. Abantu benshi batanga intungamubiri zihagije kugirango bagumane ubuzima bwiza. Indwara zimwe na zimwe z’ubuvuzi, zishobora gukumira karnitine biosynthesis cyangwa ikabuza ikwirakwizwa ryayo mu ngirabuzimafatizo, nka claudication rimwe na rimwe, indwara z'umutima, hamwe n'indwara zimwe na zimwe. Imiti imwe n'imwe irashobora kandi kugira ingaruka mbi kuri metabolisme ya karnitine mumubiri. Igikorwa cyibanze cya L-karnitine ni uguhindura lipide, cyangwa amavuta, mumavuta yingufu.
By'umwihariko, uruhare rwayo ni ukwimura aside irike muri mitochondriya ya selile eukaryotic iba muri membrane ikingira ikikije selile. Hano, aside irike ikora beta okiside hanyuma igacika kugirango ibe acetate. Ibi birori nibyo bitangiza ukwezi kwa Krebs, urukurikirane rwibinyabuzima bigoye bigira akamaro kanini kugirango bitange ingufu kuri buri selile yo mumubiri.L-karnitine nayo igira uruhare mukubungabunga ubwinshi bwamagufwa. Kubwamahirwe, intungamubiri ntizibanda cyane kumagufwa hamwe na osteocalcine, proteyine isohorwa na osteoblasts igira uruhare mumyunyu ngugu. Mubyukuri, izo nenge nizo mpamvu nyamukuru zitera osteoporose ku bagore nyuma yo gucura. Ubushakashatsi bwerekanye ko iyi miterere ishobora guhindurwa hiyongereyeho L-karnitine, ibyo bikaba byongera urugero rwa osteocalcine.
Ibindi bibazo ubuvuzi bwa L-karnitine bushobora gukemura harimo gukoresha glucose ikoreshwa cyane mu barwayi ba diyabete, kugabanya ibimenyetso bifitanye isano na syndrome de fatigue idakira, no kunoza imikorere ya tiroyide ku bantu barwaye hyperthyroidism. Hariho ibimenyetso byerekana ko propionyl-L-karnitine ishobora gufasha kunoza imikorere mibi yumugabo, ndetse no kongera imikorere ya sidenafil, imiti igurishwa munsi yikimenyetso cya Viagra. Byongeye kandi, ubushakashatsi bwerekanye ko intungamubiri zitezimbere intanga ngabo.