Imizi ya Apple ikuramo 80% Phloridzin | 85251-63-4

Ibisobanuro ku bicuruzwa:

Imizi ya pome ya pome ya pome, izina ryukuri phloretin, izina ryamahanga Dihydronaringenin, izina ryimiti ya phloretin: 3- (4-hydroxyphenyl) -1- (2, 4, 6-trihydroxyphenyl) -1-propanone.

Phloretin ni ubwoko bushya bwibintu byera uruhu ruherutse gukora ubushakashatsi no guteza imbere mumahanga. Ikwirakwizwa cyane mugishishwa nigishishwa cyimbuto zimbuto zitoshye nka pome na puwaro.

Ingaruka ninshingano za Apple Root Gukuramo 80% Phloridzin： 

Antioxidant, anti radical radical effect Ubushakashatsi bwerekanye ko phloretin ishobora guhagarika ibikorwa bya melanocytes kandi ikagira ingaruka kumurabyo ku ruhu rutandukanye.

1）Ifite ingaruka nziza yo kubuza tyrosinase, kandi ni umutekano cyane kandi ukora neza.

2）Phloretin ifite ingaruka nziza cyane kandi irashobora gukuramo inshuro 4-5 uburemere bwayo mumazi.

3) Phloretin niyongera cyane kandi ikwirakwiza transdermal penetration yongerera imbaraga, ishobora guteza imbere kwinjiza no gukoresha ibindi bintu bikora mumata, kugirango ibashe kugira ingaruka nziza.

4) Phloretin ifite ingaruka nziza zo guhagarika LOX, kubwibyo, phloretin nayo ni imiti myiza yo kurwanya umusatsi.

Ingaruka zo kurwanya inflammatory na immunosuppressive Ubushakashatsi bwakozwe bwerekanye ko kubaho k'umuriro bifitanye isano na OYA, bigaterwa kandi bigahuzwa na NO synthase, kandi OYA ikabije mu bihe by’indwara iterwa na synthase idasobanutse.

Mubikorwa bya phloretin, OYA kurekura macrophage munsi ya lipopolysaccharide na IFN-γ yagabanutse ku buryo bugaragara; igipimo cya fagocytose ya selile ya megalith nacyo cyaragabanutse cyane mubikorwa bya phloretin.

Kubwibyo, phloretin ifite ingaruka zo kurwanya inflammatory. Muri immunosuppression, phloretine ni inzitizi izwi yo guhatanira sodium D-glucose cotransporter. Kubera ko ishobora kongera umuvuduko wa lipide bilayers mu ngirabuzimafatizo, irashobora kugira uruhare mu kongera ubwoko nigikorwa cyibiyobyabwenge bitangwa muri membrane binyuze muruhu.

Kurwanya ibibyimba n'ingaruka zo kurwanya kanseriγδT selile ni ubudahangarwa bw'umubiri T selile ibaho cyane mumitsi na epiteliyale ya sisitemu yigifu, sisitemu yubuhumekero, nibindi.

Ingaruka zayo zo kurwanya ibibyimba, hiyongereyeho ibintu bimwe na bimwe bikora bisaαβT selile, nayo imenya antigene idafite molekile ya MHC. Kumenyekanisha mu buryo butaziguye poroteyine na peptide, antigene zitari peptide, hamwe n'umurimo wo gukuramo antigen no kugenzura ubudahangarwa bw'umubiri binyuze mu guhuza ingirabuzimafatizo no gusohora cytokine.