Gotu Kola Gukuramo 40% Asiaticoside | 16830-15-2

Intangiriro ya Gotu Kola ikuramo 40% Asiaticoside:

Centella asiatica, ibyatsi byose byumye bya Centella asiatica, byanditswe bwa mbere muri "Materia Medica ya Shen Nong" kandi bishyirwa ku rwego rwo hagati.

Ifite ingaruka zo gukuraho ubushyuhe nubushuhe, kwangiza no kugabanya kubyimba. Kuvura ibikomere, indwara zuruhu, nibindi.

Ibyingenzi byingenzi mubikomoka kuri Centella asiatica bishobora gukoreshwa mumavuta yo kwisiga ni acide asiatic, acide madecassic, madecassoside na madecassoside, madecassoside ni triterpenoid saponin ya Centella asiatica Nibimwe mubintu bikora bifite igipimo kinini, bingana na 30% ya glycoside yose ya Centella asiatica.

Ingaruka ninshingano za Gotu Kola ikuramo 40% Asiaticoside： 

Antibacterial

Ibikomoka kuri Centella asiatica birimo aside ya asiyatike na aside ya makasikolike, izo saponine zikora zizahindura cytoplazme mu ngirabuzimafatizo, iki gikorwa cya antibacterial kirashobora kurinda igihingwa ubwacyo kwibasirwa n’imisemburo, ubushakashatsi bwerekana ko Centella asiatica

Ibikuramo bigira ingaruka zimwe na zimwe zo kubuza Pseudomonas aeruginosa, Staphylococcus aureus na acion ya Propionibacterium.

Kurwanya inflammatory

Centella asiatica yuzuye glycoside igira ingaruka zigaragara zo kurwanya inflammatory: kugabanya umusaruro wabunzi ba pro-inflammatory (L-1, MMP-1), kunoza no gusana imikorere yinzitizi yuruhu, bityo bikarinda no gukosora imikorere mibi yumubiri wuruhu.

Gukiza ibikomere n'inkovu

Madecassoside na madecassoside nibintu byingenzi bigize Centella asiatica mukuvura ibikomere byakize.

Zishobora guteza imbere synthesis hamwe na angiogenezi mu mubiri, bigatera imikurire ya granulation nizindi nshingano zingenzi, bityo zikagira akamaro mugukiza ibikomere.

Muri icyo gihe kandi, asiaticoside igira ingaruka zo gukwirakwira kuri epidermal keratinocytes na selile endothelia selile, kandi ikagira ingaruka mbi kuri fibroblast, bityo bigatuma habaho imitsi ya granulation mugihe cyambere cyo gukira ibikomere, no kubuza inkovu mugihe cyanyuma cyo gukira. Ingaruka zo gukiza ibikomere.

Kurwanya gusaza

Ibikomoka kuri Centella asiatica birashobora guteza imbere synthesis ya kolagen I na III, hamwe no gusohora kwa mucopolysaccharide (nka synthesis ya sodium hyaluronate), kongera amazi yuruhu, gukora no kuvugurura ingirabuzimafatizo zuruhu, gutuza, kuzamura no kuzamura uruhu. Glossy.

Ku rundi ruhande, ikizamini cya ADN cyakurikiranye cyerekanye ko ikivamo cya Centella asiatica nacyo gikora ingirabuzimafatizo za fibroblast, zishobora kongera imbaraga mu ngirabuzimafatizo z’uruhu, zigakomeza uruhu rukomeye kandi rukomeye, hamwe n’iminkanyari nziza yo mu maso.

Antioxidant

Asiaticoside, acide makecassoic na acide ya makecassoic byose bifite ibikorwa bigaragara bya antioxydeant.

Ibyavuye mu bushakashatsi bw’inyamaswa byerekana ko madecassoside ishobora gutera superoxide yaho, glutathione na peroxidase mu bikomere mugihe cyambere cyo gukira ibikomere.

Urwego rwa antioxydants nka catalase, VitChing, VitE rwiyongereye ku buryo bugaragara, kandi urwego rwa lipide peroxide mu gikomere rwaragabanutseho inshuro 7.

Kwera

Asiaticoside irashobora guhagarika ibikorwa bya tyrosinase muburyo buterwa na dose, naho 4μg / ml asiaticoside ibuza tyrosinease 4%.