Flubendazole | 31430-15-6
Ibisobanuro ku bicuruzwa:
Flubenzimidazole ni insimburangingo ya benzimidazole yica udukoko ishobora kubuza kwinjiza nematode no kwegeranya microtubules yo mu nda.
Irashobora kugira isano ikomeye na tubuline (protein dimer subunit protein ya microtubules) kandi ikabuza microtubules kuva polymerisime mu ngirabuzimafatizo (ni ukuvuga ingirabuzimafatizo zo mu nda zo mu nda za nematode). Irashobora kwemezwa no kubura kwa microtubules ya cytoplasmeque no kwegeranya uduce duto twibanga muri cytoplazme kubera kwanduza kwanduye.
Nkigisubizo, ingirabuzimafatizo ya selile iba yoroheje, kandi ubushobozi bwo gusya no gufata intungamubiri buracika intege. Bitewe no kwegeranya ibintu byasohotse (hydrolase na enzymes za proteolyique), selile zandura lysis no kwangirika, amaherezo bikaviramo urupfu rwa parasite.
Gusaba:
Flubenzimidazole nudukoko twinshi twangiza udukoko dushobora kuvura neza parasite mu mbwa, nka gastrointestinal roundworms, hookworms, na whipworm; Muri icyo gihe, irashobora kandi kuvura parasite nyinshi zo mu gifu mu ngurube n’inkoko, nka Ascaris suum, Hyostrongylus rubidus, Oesophagostomum dentatum, Trichuris suis, Metastrongylus apri, nibindi.
Flubenzimidazole ntishobora kwica abantu bakuru gusa ahubwo yica amagi.
