Cytidine | 65-46-3

Cytidine ni molekile ya nucleoside igizwe na nucleobase cytosine ifitanye isano nisukari ribose. Nimwe mubice byubaka RNA (acide ribonucleic) kandi igira uruhare runini muri metabolism selile na synthesis ya nucleic aside.

Imiterere yimiti: Cytidine igizwe na pirimidine nucleobase cytosine ifatanye na karubone eshanu ya karubone ya ribose binyuze muri bond-N1-glycosidic.

Uruhare rwibinyabuzima: Cytidine nikintu cyibanze cya RNA, aho ikora nka nucleoside enye zikoreshwa mukubaka imirongo ya RNA mugihe cyo kwandukura. Usibye uruhare rwayo muri synthesis ya RNA, cytidine igira kandi uruhare munzira zitandukanye za metabolike, harimo na biosynthesis ya fosifolipide no kugenzura imvugo ya gene.

Metabolism: Imbere mu ngirabuzimafatizo, cytidine irashobora kuba fosifori kugira ngo ikore cytidine monophosphate (CMP), diphosphate cytidine (CDP), na cytidine triphosphate (CTP), ikaba ari umuhuza ukomeye muri acide nucleic aside biosynthesis hamwe nubundi buryo bwa biohimiki.

Inkomoko y'ibiryo: Cytidine iboneka mubisanzwe mu biribwa byinshi, birimo inyama, amafi, ibikomoka ku mata, n'imboga zimwe. Irashobora kandi kuboneka binyuze mumirire muburyo bwa cytidine irimo nucleotide na acide nucleic.

Ubushobozi bwo kuvura: Cytidine n'ibiyikomokaho byakorewe ubushakashatsi ku buryo bashobora kuvura mu bihe bitandukanye by'ubuvuzi, harimo indwara zifata ubwonko, kanseri, n'indwara ziterwa na virusi. Kurugero, ibigereranyo bya cytidine nka cytarabine bikoreshwa muri chimiotherapie kugirango bivure ubwoko bumwe na bumwe bwa leukemia na lymphoma.