Conotoxin | 129129-65-3

Conotoxine ni itsinda ritandukanye ryuburozi bwa peptide buto bukorwa nudusimba twa cone (genus Conus). Utwo dusimba two mu nyanja tuboneka mu nyanja zo mu turere dushyuha no mu turere dushyuha kandi tuzwiho uburyo bwihariye bwo guhiga. Udusimba twa conone dukoresha ubumara kugirango uhagarike umuhigo wabo, ugizwe ahanini n’ibindi binyabuzima byo mu nyanja nk'amafi n'inyo.

Conotoxine iboneka mu burozi bw’ibisimba kandi ikora ibintu bitandukanye, nko guhashya umuhigo no kurinda inyamaswa zangiza. Peptide iri muri conotoxine ifite ibikorwa byinshi bya farumasi kandi irashobora gukorana numuyoboro wihariye hamwe numuyoboro wa ion muri sisitemu yimitsi. Bitewe cyane cyane nintego zimwe na zimwe, conotoxine yakwegereye abashakashatsi kubishobora gukoreshwa mubuvuzi no guteza imbere ibiyobyabwenge.

Conotoxine ishyirwa mumiryango myinshi ukurikije imiterere yabyo hamwe niyakirwa ryabo bakorana. Imiryango imwe irimo:

A-conotoxine: Intego ya reseptor ya nicotinic acetylcholine.

M-conotoxine: Hagarika imiyoboro ya sodium ya sodium.

O-conotoxine: Imikoranire numuyoboro wa calcium ya gaze.

T-conotoxine: Intego ya voltage-yuzuye imiyoboro ya potasiyumu.

Ubu burozi bwerekanye amasezerano mugutezimbere imiti mishya yo gucunga ububabare, indwara zifata ubwonko, nubundi buvuzi. Abahanga bashishikajwe cyane nubushobozi bwabo bwo guhitamo guhitamo reseptor zihariye, bigatuma zishobora kuba ingirakamaro mugushushanya imiti igamije kandi ikora neza.

Ipaki:25KG / BAG cyangwa nkuko ubisabye.

Ububiko:Ubike ahahumeka, humye.

NyoboziIgipimo:Ibipimo mpuzamahanga.